SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74d41aaeca9906b0ef5d7474b20edb381f8eabb618a68ad072da50bfab8014f8' 
  AND token = 'sukeFxKGEwy5xcDRRmuKQUxJbDyGpWnWqA0jX61FAJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}