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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cc47d9dd9c655d491407cf1ef9442895dc2e201364254806daedb75df801e48' 
  AND token = 'Lm1Hcn6zCh1f4O1PqdxaRPYkW7pSvD7+aCqfdFXB8Fk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}