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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3178393bb9680ab4ecfad36d63155a20319b6e5cd4f49ba28dad11c5a80166f4' 
  AND token = 'RUKACmblYNR8yTuefG8BdDKeB6xb5RYpCT9XtJbom40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}