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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22422084e993623b7d39e350751a44ba653a88a2bdcc51df029dd75701b7a87b' 
  AND token = 'QoJ3OWYQx9VfFeNCkGlF0+xb5hd7Mbs1MJS4yEmAzCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}