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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fc1197d4526072cc342f477461dccf6a49c4425b81286252894718b1eb649a3' 
  AND token = 'jF/O2Vx0o68TaYxrHppCEpDRkEmsrIhbv0eJHrslE1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00075

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}