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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03e222eca4caca57e39047b5ccebdb4ea79aa9fb911023f26cbd04f7b92297da' 
  AND token = 'gNFOYRsc27w3dGexYM7rpFd/5Pe6l8Plkzc3xZ15fvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}