SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c286208c7cddaa18121af7516331db0dbd6bb77c7263797a1d9af5f83dc898b' 
  AND token = '1rCoW0JEKg9OIHP69IqYyfXSEhRN77+7UigQ8e041pQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}