SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16f1c2372b86907859c97184bf855a739854cdcec33ff55cc35c89e4a96f7ab3' 
  AND token = 'V8i0T9Ph8wF6R3aT0g1M88kUdW8vI7OQV4gYsnw7XOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}