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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cae0698d3d0c8b7d46cf82917f527d78dca6d80f78f286def508697b6e54afe' 
  AND token = 'UTV+x++mInLKAWNol5BiOnt5EmSt5tyuDjvJ/VZbVq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00086

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}