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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a727b0457d674d27e3235e889cdfb59c2255126c56a71bacbe0207c70f05d963' 
  AND token = 'R4Fmq5oT+oVaVTRe0AQJJ1DjZem/PG3U1Ho6EGDpIC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}