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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6689f6dddf6d56cd417977f80a9db7394d4646cf36e01dd1c3cccf69dc205905' 
  AND token = '4IAJHbzUoPI78mSqWPtBULVeXN9woVW6J3df1fGuHPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}