SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de5ac9d033f5474b7c90ae349980b6b3c41f0dd849f79a86cb856a8da859dfd3' 
  AND token = 'F1ML0MahPkB5CXFW3EL8f58ESp83oI8mTQSDhZpwDRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}