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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2570ca28325d191aa30db13b0c45859d21569f04cc2470679565acb6dc6190dd' 
  AND token = 'j4gcX1Vwy32i1jwfgE4tGWNWbPcw+24OiXQeqdlFepU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}