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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ee4b546482e219b34bca88eacca5880c142e21528e442862a4e9fa41925eb23' 
  AND token = '0U93lnkk7sPaSB4+zQIoph9wafUtVvHj3qyEHNWzSZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}