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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01ffd92921911ce54a6326c3dee07058fdc75d3f0c13b43df6621d22d758ab49' 
  AND token = 'TANoIX25pn9TyorWP3cUaHM2qLEIGEnQQoolmXboZgY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}