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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72899bf2a1ea19cc6a25b8f76f96b95248140b69c28f87ef1e4d5cc5df74f120' 
  AND token = 'v51ffZKX8n2ptDCMDLQgI0t+kx7Rl0bsHhcwuG/cCEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}