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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed5bb5b04d66f278da758fcbad1802f03d8c7ae5ba52c9ce99941dc22495d7d5' 
  AND token = '8Vt/oPRkUMEO/DIXvFQ032yBl5jv5kjjbgt16bFkKrw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}