SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75a0a47be343b2b4aee5f0c6859768ad1fc410b5105e50dd62093140ea0b1858' 
  AND token = 'oid5gORO84OUo23gMoYQeavudGJtN4xDWP2ASG6ioB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}