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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35e911b773314419e2f417e7de67f9aa3f3a6020dfa0fdb66c1236b32c376948' 
  AND token = 'tfmynO33bW1esWy1ZxkGUPhlL2N+VeMPu7uo0lrVh4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00076

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}