SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3e09d8bba10e13cff176d1fdf95c882ed680a61907db60c58c918d30a18d5b4' 
  AND token = 'UjOi5I+WrpKr/poh0ux9dmwEV7iGpEwfvWFZtVKf+L4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}