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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ed43901e8a6c9ec27fa1d9c1541f2a4f6eb64429b69db3dc00f73408d878b01' 
  AND token = 'OMsZvfxBgA8v5x3TbOBSwsO5lSxBftNLr9OOyCVePDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}