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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6509a53e645973548e54f02714bf1c030e4167f3b874e09c4798ea44a2bfe8c' 
  AND token = 'U2pk3P5r95skfX56FUGrj8WP/uuEgO8Pn3dj90LENS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}