SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '344ca9e06048ec3dbbc7654110991d0ad61e061977126270ee2e5ea2a5ccc3b9' 
  AND token = 'YuN0+Svg2OnXUv+7tFzPvVGOvBLh4kEkFAZ5QuVYuvI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}