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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f506125b0c7d7e3bb4f05a3cc223baeae29413135102346899a239d0b1c24ef' 
  AND token = '9Syh68cmZkpq/IbaJiVxM4IN0PRvCMfnpkqIValD9nI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}