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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af0ab10d6f74373e0cc0ede44183127d04cb680ad0c15da3c545718e81585ede' 
  AND token = 'VRhHwpG7VKa3v7TX7mxYIotmFz6puRMf/feXEuqY0Aw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}