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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f9e835339b1bbc7beff5f455043dff373ef27bbab0787ff907dfb7fd4020ea4' 
  AND token = 'Q2SlGyi4XjoumjAXSgq0w/sNBh1abGxvjC4Mmn8X/R8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}