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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89c84d11910dae06203403d8c5b85db2ff0e59f6d2b320afbcaff91c101dfc5d' 
  AND token = 'PnfF+8HXSrtdTL/OZTPc9Z9Uw5/jY9pGKZiazpbmqyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}