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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f5191c13cd4f87ceca4b16188336a1eb9a8bef86c1f1d9706fb0faf0d0acb24' 
  AND token = 'sqEFO2OUMbrRG3/8GrV442Wzs+SL3R7nCF+4X3GYRqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}