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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b65b0a53db3f8a0c075d44442974bf7f38aef8f5b1204b7dc72367ec0ffd7b44' 
  AND token = 'qP1KMuIF3DrHo4fM/pap+lCPexkavNQc3vRZnVDZRxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}