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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57f22205575980ef88917d51ae7a03aa07e2576322b21ab5e26e577c92517022' 
  AND token = 'iYtTGmSuHtHLK88t8pCoDROAHwhEDpTKDerOOg15XPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}