SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dc7f62621946a7a697fe25a2930f71d1cc23abe8dc2f347744dafb382d3a199' 
  AND token = 'XGEs6Sr94IRz5nNS0xjG00uuSykRSvNHdeDlTUjxUGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}