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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '708f5348d0d7d1942a9ada67628156593c3f0988907f3420e77f5cb71eebb548' 
  AND token = 'OWj/l4SS+I9zq06Ax5r0uUsxWOECO16ct1j9QOLVCUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}