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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d3871f7c8f1c3935036bc9beda7e7af738b2f1a8c08ca8b619304be249c5644' 
  AND token = 'IcGCbJo3VitKlT6VxJKqxtRcAQJGTbYpZyb+d4OTwwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}