SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13ae5e92eb0a2e2b2211a6a1c070357dc945e26bd3fce49b3b727f28de466814' 
  AND token = 'YNvTis5KVXzwgggvWmXdOwA+X2SbRNJTL/9aYH/eOgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}