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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cd8d5f6e8c1dcb01fc4e5d186a219bbd226f8df8d8837f4db5eeb8e04bf85b7' 
  AND token = 'nIG0jFshdz3YQAF1nazx+tphr5VmOZkJtExSvXKC+rk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}