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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e5bb299a9549b43e04ea9a83eea58853269889ea36780a805ac6c1de9a83053' 
  AND token = 'oOOrwGf1SEldiTOpr6+f3Yr+WRBgG//kFCnt7cjmVoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}