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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '025f8b908fd56b6605117dd7601d613f721a9c2f70681dd4f3551d0361f59645' 
  AND token = 'XQLlinO7JPPZMDMpPHPyq6m0MPbhJ2rNAGAKy6RXi5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}