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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '748077c49b40ed143f5822e32410f924edbd6a1c90a2f2b526a9291ee7557fa8' 
  AND token = 'DwfeskgmbRgRSSI9e8MaV6rlD5tuOyMNgGFNxK0Sw8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}