SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b4cf43e3a2835811d78d7d3231af991bafbcfc64d0c61c33b20a641a6a233a5' 
  AND token = '+w7RvkJKkAcYXwsqqazUDxkpu9+FDxb6FaqTsc7zKPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}