SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cd906e842e1030da810f7c3e8c8f8f62f82c0db68e061dd59b3e3cb899f8849' 
  AND token = '+6BxLiNoAd1gR3D2LyojlSER6ZrH7SgMUGCCryVQ6wA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}