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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8879a371d5421f9203cbb144d652ede13c504015a96b8adfe0a46c37bd75166b' 
  AND token = '452mj1SqbuWy/qddpeIWGzyPdJZidov34l2F5el3FyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}