SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d122f67223b2ecc9ecefc5a919f44f69a006415038a80db09cfd9f0e166c341' 
  AND token = 'Ep9L06ZjBTZYUbWFHPUiJAovErDYEI3VGTTblE7DqqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}