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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee408f4ee6a646d8160bbdfd63c5760540ac3210c92a25ca2d6da15420ad8830' 
  AND token = 'puotxs24ZmQYmxE1jwGGdYZnSuWQwft2QZ0QI8eZUTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}