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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4af655ef5569035b8e74c67a9b5e3668d9e6d85de37fd41b465e7f8cf917818' 
  AND token = 'Ak48SooyIKHDHcaqCk9WQyrB1y1fQ5ay/d/HpIl1xC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}