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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4eb8126726ff158a97189c78e2777a3b5d4d4d0077a9783140de9727d1723d8f' 
  AND token = 'LZZ9hHw75rS/9LPsmwYm2B4qvPImhyEiVZLtV4qD/m8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}