SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19528285f77b4e30aa24d94b5e52ca0edf37fde98ef501573d54d84ae5e8a57e' 
  AND token = 'MCW1dynRPTcpFdsc4D5IeoU6MIZr21rOFBmG3ewXLqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}