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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8b5c00c429ec8cb599e91d37f45a72616a03e0a04fb4d27095c61a6ce03b8a7' 
  AND token = 'yrN4g1Q5edRv4N+qbovVzq/1UNBXny+qjOSg+LJ1TS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}