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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '341178d4ca3f015bba13184ee564106fdec2cd446d76d2bd7d98b026323dad8b' 
  AND token = 'LV1Ef89/E+Vv6E2+Ip8pUYk2PXtllWBsvFYC5b/OM9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}