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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e4a172a9c13aa2bbff3206123a243b34bf0752f6354290225d80d00a49b81ff' 
  AND token = 'W27ZnNTtneQ+GhgSaEu8uXm9r1kJb9nu1Sl8lJlTbI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00084

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}