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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b860cb33cd0228c15f4cfc9a5083109a419003083359e2abc66470156e314b8' 
  AND token = 'aMFef0fjc90eInZkNPSuDWFiT/Sj/KH07UW1gyxxrCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}